WHAT WE'VE DONE
Selected Publications
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Nature, 2024 Mar;627(8005):865-872.
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Highlighted in Nature, “Astrocyte Cells in the Brain Have Immune Memory”.
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Highlighted in Immunity, “Astrocyte Remember Inflammation”.
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Highlighted in Trends in Immunology, “Astrocytes ACLYmate to Chronic Neuroinflammation”.
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Highlighted in Brigham and Women’s Hospital, “Non-Immune Brain Cells Can Acquire Immune Memory”.
Wheeler MA*, Clark IC*, Lee HG*, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ. Science, 2023 Mar 10;379(6636):1023-1030. (*denotes co-first author)
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Highlighted in Cell Systems, “Single-Cell A/B Testing for Cell-Cell Communication”.
Lee HG, Lee JU, Kim DH, Lim S, Kang IS, Choi JM. Nature Communications, 2019 Feb 12;10(1):709.
Lee HG*, Lee JH*, Flausino LE*, Quintana FJ. Science Translational Medicine, 2023 Nov 8;15(721):eadi7828. (*denotes co-first author)
Lee HG*, Wheeler MA*, Quintana FJ. Nature Reviews Drug Discovery, 2022 May;21(5):339-358. (*denotes co-first author)
2024
Droplet-Based Functional CRISPR Screening of Cell-Cell Interactions by SPEAC-seq
Akl CF, Linnerbauer M, Li Z, Lee HG, Clark IC, Wheeler MA, Quintana FJ. Nature Protocols, 2024 accepted
CLEC16A Promotes Mitophagy and Limits Disease-Promoting Astrocyte Responses
Kadowaki A, Wheeler MA, Li Z, Andersen BM, Lee HG, Illuz T, Lee JH, Ndayisaba A, Zandee SEJ, Basu H, Chao CC, Mahler JV, Klement W, Neel D, Bergstresser M, Rothhammer V, Lipof G, Srun L, Soleimanpour SA, Chiu I, Prat A, Khurana V, Quintana FJ. Nature Neuroscience, 2024 accepted
Lee HG, Quintana FJ. Nature Neuroscience, 2024 Online ahead of print.
Lee HG, Quintana FJ. Molecular Cell, 2024 Jul 25;84(14):2596-2597.
Lim S, J F van Son G, Wisma Eka Yanti NL, Andersson-Rolf A, Willemsen S, Korving J, Lee HG, Begthel H, Clevers H.
Cell Reports, 2024 Mar 27;43(4):114019.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Nature, 2024 Mar;627(8005):865-872.
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Highlighted in Nature, “Astrocyte Cells in the Brain Have Immune Memory”.
-
Highlighted in Immunity, “Astrocyte Remember Inflammation”.
-
Highlighted in Trends in Immunology, “Astrocytes ACLYmate to Chronic Neuroinflammation”.
-
Highlighted in Brigham and Women’s Hospital, “Non-Immune Brain Cells Can Acquire Immune Memory”.
2023
Lee HG*, Lee JH*, Flausino LE*, Quintana FJ. Science Translational Medicine, 2023 Nov 8;15(721):eadi7828.
(*denotes co-first author)
Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Nature, 2023 Aug;620(7975):881-889.
Cho MJ*, Lee HG*, Yoon JW, Kim GR, Koo JH, Taneja R, Edelson BT, Lee YJ, Choi JM. Experimental & Molecular Medicine, 2023 May 1. (*denotes co-first author)
Wheeler MA*, Clark IC*, Lee HG*, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ. Science, 2023 Mar 10;379(6636):1023-1030. (*denotes co-first author)
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Highlighted in Cell Systems, “Single-Cell A/B Testing for Cell-Cell Communication”.
Clark IC*, Wheeler MA*, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, Rone JM, Giovannoni F, Charabati M, Akl CF, Aleman DM, Zandee SJ, Prat A, Douek DC, Boritz EA, Quintana FJ†, Abate AR†. Nature, 2023 Feb;614(7947):326-333.
2022
Sanmarco LM*, Chao CC*, Wang YC*, Kenison JE*, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Masconfroni I, Jaronene M, Alsuwailm M, Hewson P, Yeste A, Anderson BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Nature, 2022 Nov;611(7937):801-809.
Lee HG*, Wheeler MA*, Quintana FJ. Nature Reviews Drug Discovery, 2022 May;21(5):339-358. (*denotes co-first author)
2021
Kim GR*, Kim WJ*, Lim S*, Lee HG, Koo JH, Nam KH, Kim SM, Park SD, Choi JM. Advanced Science, 2021 May 05;8(14):2004973.
2020
Lee HG*, Cho MJ*, Choi JM. Experimental & Molecular Medicine, 2020 Aug;52(8):1255-1263. (*denotes co-first author)
Lee HG*, Kim LK*, Choi JM. Molecular Therapy Methods & Clinical Development, 2020 Mar 13;16:32-41.
(*denotes co-first author)
2019
Kim DH, Lee HG, Choi JM. Immune Network, 2019 Oct 17;19(5):e35.
Lee HG, Lee JU, Kim DH, Lim S, Kang IS, Choi JM. Nature Communications, 2019 Feb 12;10(1):709.
2015 - 2018
Kim DH, Park HJ, Lim S, Koo JH, Lee HG, Choi JO, Oh JH, Ha SJ, Kang MJ, Lee CM, Lee CG, Elias JA, Choi JM.
Nature Communications, 2018 Feb 5;9(1):503.
Protein Tyrosine Phosphatase Conjugated with a Novel Transdermal Delivery Peptide,
AP-rPTP Alleviates Both Atopic Dermatitis-like and Psoriasis-like Dermatitis
Kim WJ*, Koo JH*, Cho HJ, Lee JU, Kim JY, Lee HG, Lee S, Kim JH, Oh MS, Suh M, Shin EC, Ko JY, Sohn MH, Choi JM.
Journal of Allergy and Clinical Immunology, 2018 Jan;141(1):137-151.
Lim S*, Kim WJ*, Kim YH, Lee SH, Kim HM, Park HJ, Koo JH, Lee HG, Yoon HS, Kim DH, Lee JA, Kim JY, Shin JH, Kim LK, Doh JS, Kim H, Bothwell AB, Lee SK, Suh M, Choi JM. Nature Communications, 2015 Sep 15;6:8244.